Microorganisms causing wound infection and their antibiotic susceptibility pattern

Background: Pyogenic infection is one of major causes morbidity and increasing medical expense. Multiple organisms can cause wound infection. Drug resistant bacteria are the most important therapeutic challenge.Methods: A prospective study was carried out from July 2021 to October 2021and pus samples were collected suspected OPD indoor patients with The specimen after appropriate aerobic culture, grown identified by colony morphology, staining reaction different standard biochemical tests. Modified Kirby Bauer disc diffusion method used for antimicrobial susceptibility testing.Results: Out 140 patients, 88 (62.9%) showed bacterial growth them male 66 (64.70%). Most isolates isolated in-patient (52, 59.1%). Staphylococcus aureus prevalent pathogen (38.6%) followed Klebsiella spp. (22.7%). S. MRSA (32.4%) sensitive vancomycin, linezolid teicoplanin. other Gram-negative mostly imipenem they highly co-trimoxazole, cephalosporins.Conclusions: mainly attributing pyogenic infections aureus, species. High level drug resistance seen both Gram positive bacteria. Continuous surveillance necessary. As microorganisms antibiotic classes, so effective proper implementation local policy needed.